Evidence of Migration of Ingested Asbestos into Various Baboon Organs

1980:121: Millette

SEM/1980/I:347-354

Abstract:

This report presents the results of transmission electron microscopic analysis for asbestos in ten organs of the newborn baboon who was orally administered with chrysotile asbestos. The feeding period consisted of 9 days with a cumulative dose of 3 x 1013 chrysotile fibers per kilogram. Analysis of the same ten organs of a control newborn baboon is also included. The test tissues showed higher levels of asbestos than respective control tissues. The highest concentration of chrysotile fibers was found in the kidney cortex followed by lymph nodes, spleen, colon, esophagus, kidney medulla, stomach, and liver. Fiber size distribution of the fibers recovered indicated that the longest fiber was retained in the kidney cortex.

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